Response: A Quest and a Wager
نویسندگان
چکیده
Jed Rose: I think we are far from exploiting the full potential of nicotine itself as a replacement for smoking. At present, fewer than 10 percent of people using nicotine replacement therapy (NRT) achieve longterm smoking cessation. I think the success rate is low because we haven’t yet learned to administer nicotine in a way that reproduces the full effect of nicotine obtained from smoking. Along with acute reinforcement, stress reduction, and cognitive enhancement, we also need to address the habit component—the constellation of sensory cues that develop around inhaling smoke. Kenny: Do you believe that it’s a viable strategy to consider medications that bypass the nicotinic receptor and instead work on other systems, like GABA and glutamate, that underlie the habitual aspects of smoking behavior?
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2011